cobicistat will boost the level or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. A decreased dose of diazepam can be demandedcrofelemer improves levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Crofelemer has the prospective to in